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Epidermal growth factor receptor (EGFR) and EGFR variant III (EGFRvIII) immunohistochemistry of a patient with glioblastoma multiforme (GBM). Staining with (A) EGFR and (B) EGFRvIII before vaccine. (C) Preservation of EGFR staining but (D) specific loss of EGFRvIII staining at recurrence after vaccination.
