FIGURE 4.
Effects of siRNA-mediated suppression of ARNT/HIF-1β on glycolytic metabolite levels (A) and TCA cycle intermediates (B) in 832/13 cells. Data are presented as a ratio of target metabolite corrected for an internal control (myristic acid-d27) and represents mean ± S.E. of 3 independent experiments. LG, low glucose (2 mm); HG, high glucose (16.7 mm). *, p < 0.05, HG siControl versus HG siARNT1; **, p < 0.01; ***, p < 0.01, HG siControl versus HI siARNT1; #, p < 0.05; ##, p < 0.01, LG siControl versus LG siARNT1.
