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Inhibition of the RecA intein by different classes of platinum(II) compounds
| Number | Complexes | Class | IC50 |
|---|---|---|---|
| μm | |||
| 1 | Cisplatin | cis | 2.5 |
| 2 | Pt(Phen)Cl2 | cis | 10 |
| 3 | Oxaliplatin | cis | 23 |
| 4 | Carboplatin | cis | 30 |
| 5 | cDPCP | Mono | 50 |
| 6 | Pt(NH3)2(im)Cl | Mono | 77 |
| 7 | Pt(NH3)2(3-py-CH2OH)Cl | Mono | 120 |
| 8 | trans-DDP | trans | >200 |
| 9 | trans-EE | trans | >200 |
