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. 2010 Nov 5;286(2):1374–1380. doi: 10.1074/jbc.M110.144097

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FIGURE 2. — Oxo-aldehyde formation and detoxification of (M)GO in the blood of wild-type and transgenic GLO-I rats. Glyoxal (A), MGO (B), and 3-DG (C) levels in the blood of WtC, TgC, WtD, and TgD rats are shown. A composite score was calculated for the GLO-I- sensitive oxo-aldehydes GO and MGO (D). d-Lactate levels in the plasma (E) and urine (F) of the WtC, TgC, WtD, and TgD rats are shown. *, p < 0.05 compared with control; **, p < 0.01 compared with control; ***, p < 0.001 compared with control; #, p < 0.05 compared with wild-type diabetic.