Sequence alignment of HugZ, Cj1613c, HI0854, and some of the smaller heme-utilization proteins. Residues in bold font with black background are completely conserved. Residues in bold font with white background are highly conserved. Proteins used in the alignment are (from top to bottom): H. pylori HugZ, C. jejuni protein Cj1613c, H. influenzae protein HI0854, Photobacterium sp. SKA34 HugZ, Vibrio alginolyticus protein V12G01-06051, Shewanella sp. ANA-3, Pasteurella multocida subsp. multocida str. Pm70 PM0299, Aeromonas hydrophila subsp. hydrophila ATCC 7966 HutZ, Histophilus somni HutZ, Aliivibrio salmonicida LFI1238 HuvZ, Mannheimia hemolytica PHL213 HugZ, Plesiomonas shigelloides HugZ, and Vibrio cholerae HutZ.