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LOXL2 expression as a function of fracture healing is unique among LOX isoforms. Expression of LOX mRNA (A) and its isoforms LOXL1-LOXL4 (B–E, respectively) in normal fracture healing was determined by real-time qPCR. RNA was collected from healing fractures from 3 mice per time point and RNAs pooled; LOX and LOXL1–4 mRNA expressions were normalized to glyceraldehyde-3-phosphate dehydrogenase mRNA levels. Data are expressed as fold change relative to day 0.
