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LOXL2 expression in epiphyseal growth plates. Paraffin-embedded sections of the growth plates from 7- and 14-day-old mice were immunostained for LOXL2 as described under “Experimental Procedures.” Positive staining is seen in proliferating (P), hypertrophic (H), and calcifying (C) chondrocytes. A day 14 non-immune IgG control counterstained with hematoxylin is shown; scale bar, 10 μm, photographed at 20× magnification.
