Table 1. Summary of clinical findings of glaucoma patients.
| (a) Patient no 1 | Age: 25 | Diagnosis: pigmentary dispersion glaucoma |
| Right eye | Left eye | |
| Visual acuity | ▶ 20/15 | ▶ 20/15 |
| Colour vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Within normal limits, foveal threshold of 37 dB, MD of −1.67 dB | ▶ Superior arcuate defect, inferior partial arcuate defect, foveal threshold of 37 dB, MD of −16.37 dB |
| IOP (mm Hg) | ▶ 15 | ▶ 17 |
| Refractive error | ▶ −1.50 D (sphere) | ▶ −1.75 D (sphere) |
| Fundus | ▶ 0.7 C/D ratio with no notching—see supplementary figure 1A | ▶ 0.85 C/D ratio with pallor in the cup and narrow rim—see supplementary figure 1A |
| (b) Patient no 2 | Age: 48 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20-1 | ▶ 20/20-1 |
| Colour vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Within normal limits, foveal threshold of 35 dB, MD of −0.28 dB | ▶ Inferior nasal step, foveal threshold of 36 dB, MD of −1.49 dB |
| IOP (mm Hg) | ▶ 12 | ▶ 13 |
| Refractive error | ▶ −6.50+0.50×70 | ▶ −6.50+1.00×95 |
| Fundus | ▶ 0.6 C/D ratio, normal fundus—see supplementary figure 1B | ▶ 0.8 C/D ratio with superior notch with a focal NFL defect—see supplementary figure 1B |
| (c) Patient no 3 | Age: 33 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20 | ▶ 20/20 |
| Colour vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Within normal limits, foveal threshold of 39 dB, MD of 0.00 dB | ▶ Superior arcuate defect, foveal threshold of 40 dB, MD of −10.77 dB |
| IOP (mm Hg) | ▶ 15 | ▶ 8 |
| Refractive error | ▶ −8.75+1.00×105 | ▶ −9.00+3.50×87 |
| Fundus | ▶ 0.8 C/D ratio—see supplementary figure 1C | ▶ 0.9 C/D ratio—see supplementary figure 1C |
| (d) Patient no 4 | Age: 63 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20-1 | ▶ 20/30 |
| Colour vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Superior nasal step, foveal threshold of 35 dB, MD of −5.21 dB | ▶ Inferior nasal step, foveal threshold of 33 dB, MD of −4.09 dB |
| IOP (mm Hg) | ▶ 14 | ▶ 12 |
| Refractive error | ▶ +1.50 +0.75×180 | ▶ +1.00 D (sphere) |
| Fundus | ▶ 0.75 C/D ratio with thin rim and peripapillary atrophy, no disc haemorrhage, vitreous syneresis—see supplementary figure 1D | ▶ 0.8 C/D ratio with thin rim and peripapillary atrophy, no disc haemorrhage, vitreous syneresis—see supplementary figure 1D |
| (e) Patient no 5 | Age: 57 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20 | ▶ 20/15-2 |
| Colour Vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Superior partial arcuate defect, foveal threshold of 36 dB, MD of −8.35 dB | ▶ Within normal limits, foveal threshold of 36 dB, MD of −0.75 dB |
| IOP (mm Hg) | ▶ 12 | ▶ 12 |
| Refractive error | ▶ −3.25+0.50×100 | ▶ −4.00+0.75×72 |
| Fundus | ▶ 0.8 C/D ratio with a focal NFL defect, small disc haemorrhage—see supplementary figure 1E | ▶ 0.7 C/D ratio with inferior temporal thinning of the rim, no disc haemorrhage—see supplementary figure 1E |
| (f) Patient no 6 | Age: 55 | Diagnosis: POAG |
| Visual acuity | ▶ 20/15-2 | ▶ 20/15-2 |
| Colour vision | ▶ Within normal limits | ▶ Within normal limits |
| VF | ▶ Within normal limits, foveal threshold of 38 dB, MD of −0.28 dB | ▶ Within normal limits, foveal threshold of 36 dB, MD of −0.56 dB |
| IOP (mm Hg) | ▶ 15 | ▶ 17 |
| Refractive error | ▶ −4.75+0.50×95 | ▶ −6.25+1.50×75 |
| Fundus | ▶ 0.6 C/D ratio with inferior notch, no disc haemorrhage—see supplementary figure 1F | ▶ 0.4 C/D ratio—see supplementary figure 1F |
| (g) Patient no 7 | Age: 56 | Diagnosis: NTG |
| Visual Acuity | ▶ 20/20 | ▶ 20/20 |
| Colour vision | ▶ Abnormally high tritan scores | ▶ Abnormally high tritan scores |
| VF | ▶ Within normal limits, foveal threshold of 36 dB, MD of +0.07 dB | ▶ Inferior partial arcuate defect, foveal threshold of 36 dB, MD of −4.95 dB |
| IOP (mm Hg) | ▶ 13 | ▶ 13 |
| Refractive error | ▶ −5.25+1.00×180 | ▶ −4.75+0.75×25 |
| Fundus | ▶ 0.6 C/D ratio with no disc haemorrhage—see supplementary figure 1G | ▶ 0.7 C/D ratio with disc haemorrhage at 1 o'clock position—see supplementary figure 1G |
| (h) Patient no 8 | Age: 50 | Diagnosis: NTG |
| Visual acuity | ▶ 20/25-2 | ▶ 20/20-2 |
| Colour vision | ▶ Not available for testing | ▶ Not available for testing |
| VF | ▶ Superior arcuate defect, foveal threshold of 37 dB, MD of −4.54 dB | ▶ Within normal limits, foveal threshold of 38 dB, MD of+0.25 dB |
| IOP (mm Hg) | ▶ 14 | ▶ 20 |
| Refractive error | ▶ +2.00 +1.00×146 | ▶ +1.00+0.50×43 |
| Fundus | ▶ 0.8 C/D ratio with disc haemorrhage at 8-9 o'clock position—see supplementary figure 1H | ▶ 0.8 C/D ratio with disc haemorrhage at 5 o'clock position—see supplementary figure 1H |
| (i) Patient no 9 | Age: 78 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20-1 | ▶ 20/20 |
| Colour vision | ▶ Not available for testing | ▶ Not available for testing |
| VF | ▶ Superior arcuate defect as well as inferior partial arcuate defect, foveal threshold of 36 dB, MD of −15.09 dB | ▶ Inferior partial arcuate defect, foveal threshold of 35 dB, MD of −6.72 dB |
| IOP (mm Hg) | ▶ 18 | ▶ 17 |
| Refractive error | ▶ −0.25+0.50×167 | ▶ +0.25+0.50×175 |
| Fundus | ▶ 0.9 C/D ratio with loss of rimdsee supplementary figure 1I | ▶ 0.9 C/D ratio with loss of rim—see supplementary figure 1I |
| (j) Patient no 10 | Age: 57 | Diagnosis: POAG |
| Visual acuity | ▶ 20/20 | ▶ 20/20 |
| Colour vision | ▶ Abnormally high tritan scores | ▶ Abnormally high tritan scores |
| VF | ▶ Superior arcuate defect involving fixation, foveal threshold of 36 dB, MD −2.74 dB | ▶ Within normal limits, foveal threshold of 33 dB, MD of −1.84 dB |
| IOP (mm Hg) | ▶ 13 | ▶ 11 |
| Refractive error | ▶ −2.00+1.00×050 | ▶ −4.75+3.50×162 |
| Fundus | ▶ 0.8 C/D ratio with 360° peripapillary atrophy, thinning of rim in the inferior temporal region—see supplementary figure 1J | ▶ 0.6 C/D ratio with normal optic nerve rim—see supplementary figure 1J |
C/D, cup to disc; IOL, intraocular lens; NFL, nerve fibre layer; NTG, normal tension glaucoma; POAG, primary open-angle glaucoma; VF, visual field.