Figure 5. Simulations of viral genomic diversification with a low frequency of multiple infections.

The evolution of (A) viral diversity, d_G, (B) divergence, d_S, and (C) average fitness, f, with generations predicted by our simulations for different population sizes, C. Each cell is assumed to be infected with M virions drawn from a distribution based on a viral dynamics model (see text). Error bars represent standard deviations.