Table 1.
Characteristic | D (n = 207) | MCI (n = 190) | ND (n = 934) | P-Value | P-Value DvsND | P-Value MCI vs ND | P-Value D vs MCI |
---|---|---|---|---|---|---|---|
Follow-up, years, mean ± SD | 6.1 ± 3.3 | 6.2 ± 3.4 | 6.5 ± 2.8 | .16 | — | — | — |
Age, mean ± SD | 84.0 ± 6.6 | 83.4 ± 6.1 | 81.6 ± 4.7 | <.001 | <.001 | <.001 | .21 |
Female, N (%) | 149 (72.0) | 120 (63.2) | 682 (73.0) | .02 | .76 | .006 | .06 |
Education, years, mean ± SD | 10.0 ± 3.2 | 10.3 ± 2.9 | 12.0 ± 2.4 | <.001 | <.001 | <.001 | .32 |
BMI, kg/m2, mean ± SD | |||||||
Women | 26.4 ± 7.0 | 26.2 ± 5.7 | 28.4 ± 5.7 | — | |||
Men | 26.4 ± 3.5 | 26.6 ± 6.0 | 27.5 ± 4.9 | ||||
Drink alcohol, n (%) | .14 | — | — | — | |||
Never | 78 (37.7) | 60 (31.6) | 318 (34.1) | ||||
Current | 22 (10.6) | 30 (15.8) | 164 (17.6) | ||||
Past | 107 (51.7) | 100 (52.6) | 452 (48.4) | ||||
Smoker, n (%) | .009 | .15 | .003 | .30 | |||
Never | 91 (44.0) | 70 (36.8) | 412 (44.1) | ||||
Current | 28 (13.5) | 33 (17.4) | 86 (9.2) | ||||
Past | 88 (42.5) | 87 (45.8) | 436 (46.7) | ||||
History of, n (%) | |||||||
Cancer | 41 (19.8) | 37 (19.6) | 222 (23.8) | .27 | — | — | — |
Hypertension | 186 (90.3) | 171 (91.0) | 882 (95.5) | .003 | .003 | .01 | .82 |
Diabetes mellitus | 62 (30.0) | 67 (35.3) | 336 (36.0) | .26 | — | — | — |
Heart attack | 68 (32.9) | 65 (34.2) | 256 (27.4) | .08 | — | — | — |
Stroke | 65 (31.4) | 53 (27.9) | 158 (16.9) | <.001 | <.001 | <.001 | .44 |
Depression | 47 (22.7) | 40 (21.1) | 156 (16.7) | .07 | — | — | — |
Information was collected at the time of diagnosis for participants with dementia and MCI and at the 2007 evaluation for participants with normal cognition.
SD = standard deviation; BMI = body mass index.