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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Appl Toxicol. 2010 Oct 8;31(3):242–254. doi: 10.1002/jat.1586

Table 1.

Maternal effects after exposure to 50µg/kg cylindrospermopsin.

Exposure Treatment # Mice # Died(%) Bleeding (#)a
Vaginal Orbital Tail Gastrointestinal
GD 8–12 control 26   0 0 0 0 0
cyn 42 23(55)b,c,d 13 2 2 0
GD 13–17 control 26   0 0 0 0 0
cyn 42   0 0 1 0 3e
a

Multiple effects occurred in single animals

b

p<0.01

c

Includes 8 animals killed when moribund (GD13)

d

5 (GD12); 8 (GD13); 1 (GD16); 1 (GD18)

e

2 instances of intestinal bleeding were noted in the 4 animals killed on GD 13 and 1 instance was seen 7 days post dosing