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. 2010 Dec 27;108(2):774–779. doi: 10.1073/pnas.1011845108

Fig. 3.

Fig. 3.

Ablation of Rarb affects the composition of the stroma. (A) Paraffin-embedded sections derived from MMTV-ErbB2 tumors in the wild-type and Rarb−/− backgrounds stained for RARβ. (B) Paraffin-embedded sections stained for α-SMA (red, cytoplasmic). Quantification of positive cells is shown on the right (*P < 0.001). (C) Paraffin-embedded sections costained for RARβ (red, nuclear) and α-SMA (blue, cytoplasmic). (D) Paraffin-embedded mammary tumor sections stained for Stat1. Quantification of positive cells is shown on the right (*P < 0.001). Arrows in A, C, and D point to positive cells. [Scale bars (A–D): 50 μm for low magnification (Left) and 20 μm for high magnification (Right).] (E) Western blot analysis of Stat1 and phosphorylated Stat1 (pStat1).