Table 3. Risk Estimates of Colorectal Adenoma for Sleep Duration, Sleep Apnea, and Shift Work.

		Base Model Logistic Regression‡		Full Model Logistic Regression *		Full Model Logistic Regression with HOMA-IR**
	Cases/ Controls	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
Average Hours Sleep Per Night			0.013§		0.023§		0.027§
>7	136/437	1.00 (referent)		1.00 (referent)		1.00 (referent)
6-7	100/256	1.24 (0.91-1.69)		1.24 (0.90-1.70)		1.40 (0.98-2.00)
<6	95/198	1.50 (1.08-2.09)		1.47 (1.05-2.06)		1.49 (1.02-2.19)
Sleep Apnea Diagnosis	33/58	1.39 (0.88-2.43)	0.16	1.37 (0.84-2.23)	0.20	1.44 (0.84-2.47)	0.19
Ever worked alternate shift	182/414	1.18 (0.91-1.54)	0.22	1.12 (0.85-1.48)	0.43	1.16 (0.85-1.59)	0.35

^†Compared to those averaging at least 6 hours of sleep per night

^‡Logistic regression odds ratio and p-value, accounting for age, gender and race (338 cases and 902 controls)

^*Logistic regression odds ratio and p-value, accounting for age, gender, race, income, smoking (ever/never/current), family history of colorectal cancer (yes/no) and waist-to-hip ratio (338 cases and 902 controls)

^**Logistic regression odds ratio and p-value, accounting for age, gender, race, income, smoking (ever/never/current), family history of colorectal cancer (yes/no), waist-to-hip ratio and HOMA-IR (266 cases and 745 controls)

^§p for trend