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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Am J Cardiol. 2011 Jan;107(1):41–46. doi: 10.1016/j.amjcard.2010.08.041

Table 3.

Demographic Characteristics Associated with Aspirin Use at Follow-up (2005-2007), by Framingham Risk Score*

Variable Prevalence of Aspirin Use Adjusted Odds Ratio of Aspirin Use (95% CI)

Low
Risk
P Increased
Risk
P High
Risk
P Low Risk P Increased
Risk
P High Risk P
Overall population 23% 31% 44%
Age (years) < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
 45-54 13% 19% 30% 1.00 1.00 1.00
 55-64 22% 27% 37% 2.1 (1.5-3.1) 2.1 (1.2-4.0) 1.4 (1.0-2.1)
 65-74 30% 36% 47% 2.9 (2.0-4.4) 4.8 (2.3-10.3) 2.5 (1.7-3.6)
 75-90 38% 42% 48% 4.5 (2.7-7.4) 6.4 (2.7-15.1) 3.0 (2.0-4.4)
Women 23% 0.09 35% 0.05 44% 0.66 1.00 0.55 1.00 0.09 1.00 0.04
Men 17% 27% 44% 1.2 (0.7-2.1) 1.7 (0.9-3.0) 1.2 (1.0-1.5)
White 29% < 0.001 41% < 0.001 53% < 0.001 1.00 < 0.001 1.00 < 0.01 1.00 < 0.001
Black 19% 27% 43% 0.5 (0.4-0.7) 0.5 (0.3-0.8) 0.6 (0.5-0.7)
Hispanic 20% 24% 38% 0.6 (0.4-0.8) 0.6 (0.3-1.0) 0.6 (0.4-0.7)
Chinese 14% 15% 28% 0.4 (0.3-0.6) 0.3 (0.1-0.6) 0.3 (0.2-0.4)
Diabetes mellitus NA NA < 0.001 NA NA < 0.001
 No 23% 31% 41% NA NA 1.00
 Yes NA NA 51% NA NA 2.2 (1.8-2.7)
Medical insurance < 0.001 0.01 < 0.001 NA NA NA
 No 9% 14% 21% NA NA NA
 Yes 24% 33% 45% NA NA NA
Income ($) 0.89 0.50 0.01 0.66 0.87 0.17
 < 12 000 23% 23% 38% 1.00 1.00 1.00
 12 000-24 999 22% 34% 42% 0.9 (0.5-1.4) 1.4 (0.6-2.9) 1.1 (0.8-1.5)
 25 000-49 999 24% 30% 42% 1.0 (0.6-1.6) 1.2 (0.6-2.4) 1.0 (0.8-1.4)
 ≥ 50 000 22% 32% 47% 0.8 (0.5-1.3) 1.3 (0.6-2.7) 1.3 (0.9-1.8)
Education 0.45 0.01 0.04 0.79 0.32 0.52
 < High school 21% 18% 39% 1.00 1.00 1.00
 High school 26% 38% 43% 1.1 (0.7-1.8) 1.8 (0.8-3.9) 1.0 (0.8-1.4)
 > High school 23% 33% 45% 1.0 (0.7-1.6) 1.7 (0.8-3.4) 1.1 (0.9-1.5)

CI = Confidence Interval, NA = Not Applicable

*

The Framingham risk scores were stratified into three mutually exclusive categories based on the United States Preventive Services Task Force and American Heart Association guidelines from 2002: low risk (< 6%), increased risk (6% to 9.9%), and high risk (≥ 10%)

Chi square tests for trend

Wald test from logistic regression models (age, gender, race/ethnicity, diabetes mellitus, income, and education included in models)