Table 3.
Demographic Characteristics Associated with Aspirin Use at Follow-up (2005-2007), by Framingham Risk Score*
| Variable | Prevalence of Aspirin Use | Adjusted Odds Ratio of Aspirin Use (95% CI) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low Risk |
P† | Increased Risk |
P | High Risk |
P | Low Risk | P‡ | Increased Risk |
P | High Risk | P | |
| Overall population | 23% | 31% | 44% | |||||||||
| Age (years) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | ||||||
| 45-54 | 13% | 19% | 30% | 1.00 | 1.00 | 1.00 | ||||||
| 55-64 | 22% | 27% | 37% | 2.1 (1.5-3.1) | 2.1 (1.2-4.0) | 1.4 (1.0-2.1) | ||||||
| 65-74 | 30% | 36% | 47% | 2.9 (2.0-4.4) | 4.8 (2.3-10.3) | 2.5 (1.7-3.6) | ||||||
| 75-90 | 38% | 42% | 48% | 4.5 (2.7-7.4) | 6.4 (2.7-15.1) | 3.0 (2.0-4.4) | ||||||
| Women | 23% | 0.09 | 35% | 0.05 | 44% | 0.66 | 1.00 | 0.55 | 1.00 | 0.09 | 1.00 | 0.04 |
| Men | 17% | 27% | 44% | 1.2 (0.7-2.1) | 1.7 (0.9-3.0) | 1.2 (1.0-1.5) | ||||||
| White | 29% | < 0.001 | 41% | < 0.001 | 53% | < 0.001 | 1.00 | < 0.001 | 1.00 | < 0.01 | 1.00 | < 0.001 |
| Black | 19% | 27% | 43% | 0.5 (0.4-0.7) | 0.5 (0.3-0.8) | 0.6 (0.5-0.7) | ||||||
| Hispanic | 20% | 24% | 38% | 0.6 (0.4-0.8) | 0.6 (0.3-1.0) | 0.6 (0.4-0.7) | ||||||
| Chinese | 14% | 15% | 28% | 0.4 (0.3-0.6) | 0.3 (0.1-0.6) | 0.3 (0.2-0.4) | ||||||
| Diabetes mellitus | NA | NA | < 0.001 | NA | NA | < 0.001 | ||||||
| No | 23% | 31% | 41% | NA | NA | 1.00 | ||||||
| Yes | NA | NA | 51% | NA | NA | 2.2 (1.8-2.7) | ||||||
| Medical insurance | < 0.001 | 0.01 | < 0.001 | NA | NA | NA | ||||||
| No | 9% | 14% | 21% | NA | NA | NA | ||||||
| Yes | 24% | 33% | 45% | NA | NA | NA | ||||||
| Income ($) | 0.89 | 0.50 | 0.01 | 0.66 | 0.87 | 0.17 | ||||||
| < 12 000 | 23% | 23% | 38% | 1.00 | 1.00 | 1.00 | ||||||
| 12 000-24 999 | 22% | 34% | 42% | 0.9 (0.5-1.4) | 1.4 (0.6-2.9) | 1.1 (0.8-1.5) | ||||||
| 25 000-49 999 | 24% | 30% | 42% | 1.0 (0.6-1.6) | 1.2 (0.6-2.4) | 1.0 (0.8-1.4) | ||||||
| ≥ 50 000 | 22% | 32% | 47% | 0.8 (0.5-1.3) | 1.3 (0.6-2.7) | 1.3 (0.9-1.8) | ||||||
| Education | 0.45 | 0.01 | 0.04 | 0.79 | 0.32 | 0.52 | ||||||
| < High school | 21% | 18% | 39% | 1.00 | 1.00 | 1.00 | ||||||
| High school | 26% | 38% | 43% | 1.1 (0.7-1.8) | 1.8 (0.8-3.9) | 1.0 (0.8-1.4) | ||||||
| > High school | 23% | 33% | 45% | 1.0 (0.7-1.6) | 1.7 (0.8-3.4) | 1.1 (0.9-1.5) | ||||||
CI = Confidence Interval, NA = Not Applicable
The Framingham risk scores were stratified into three mutually exclusive categories based on the United States Preventive Services Task Force and American Heart Association guidelines from 2002: low risk (< 6%), increased risk (6% to 9.9%), and high risk (≥ 10%)
Chi square tests for trend
Wald test from logistic regression models (age, gender, race/ethnicity, diabetes mellitus, income, and education included in models)