TABLE IV.
Parameter | True value |
SE of parameter estimates |
Mean estimated SE |
True SE |
---|---|---|---|---|
β X | 1.099 | 0.308* | 0.284 | 0.293 |
β A1 | 0.693 | 0.073 | 0.092 | 0.092 |
β AX1 | 0.693 | 0.266* | 0.255 | 0.252 |
β A2 | 0.000 | 0.076 | 0.081 | 0.082 |
β AX2 | 0.693 | 0.308* | 0.278 | 0.278 |
Genotype is simulated at the two marker loci with PMi = 0.25, i = 1,2. The environmental covariate (X) is Normal (0, 0.1). The measurement error is additive with variance of noise that is 0.25.
The data are simulated and analyzed under the additive effect model. 5%-trimmed values are marked by *. The results are based on 500 samples of 1,000 cases and 1,000 controls.