Figure 3.
LVEDD (A), ejection fraction (B), and fractional shortening (C) are dependent on time-of-day of I/R. All measures were performed following one month of reperfusion. LVEDD was assessed by H&E staining. Ejection fraction and fractional shortening were assessed by echocardiography. Data are shown as means ± SEM for 3 (A) or 6 (B/C) hearts per group. *P<0.05 Sham vs. I/R within genotype and ZT; $P<0.05 WT vs. CCM within procedure and ZT; #P<0.05 ZT0 vs. ZT12 within procedure and genotype; §P=0.056 ZT0 vs. ZT12 within procedure and genotype; ‡P=0.058 ZT0 vs. ZT12 within procedure and genotype.