TABLE 2.
Definition and summary of characteristics of the Af2 clonal complex of M. bovis
| Category | Description |
|---|---|
| Definition | Presence of deletion RDAf2 (14.1 kb between Mb0599 and Mb0610) |
| Spoligotype marker | Absence of spacers 3 to 7 |
| Spoligotype signaturea | 1100000101111110111111111111111111111100000 (SB0133) |
| Distribution | At high frequency in East Africa (Uganda, Burundi, Tanzania, and Ethiopia) |
| IS6110 copy no. | 4 or more copies (infrequently less than 4) |
a
The spoligotype signature represents the assumed spoligotype pattern in the progenitor strain of this clonal complex and is shown as a series of 43 ones and zeros corresponding to spacers 1 to 43 in spoligotyping, with “1” representing hybridization to the spacer and “0” representing absence of hybridization. The international name for this spoligotype pattern was assigned by Mbovis.org (http://www.mbovis.org).