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. 2010 Nov 3;66A(2):170–178. doi: 10.1093/gerona/glq169

Figure 4.

Figure 4.

(A) Log of odds ration (LOD) plots of interval mapping in the 200-, 500-, and 800-day old B6D2F2 intercross; black line is 200 days, gray solid line is 500 days, and dashed black line is 800-day age group. Thresholds of significance marked by horizontal dotted lines were determined by 10,000 permutations. The suggestive and significant thresholds for TTBT were 3.1 and 4.8 for 200 days of age, 3.1 and 4.9 for 500 days of age, and 3.1 and 4.9 for 800 days of age, respectively. (B) Separate LOD plots of interval mapping of the 200, 500, and 800 days of age in the BxD RI strains. Thresholds of significance marked by the horizontal dotted lines were determined by 10,000 permutations. The suggestive thresholds for TTBT at all three ages were 2.6. The significant thresholds for TTBT were 3.9 at 200 days of age and 3.7 for 500 and 800 days of age.