Table 2.
Statistical Estimates of Survival Differences Between Control and Rapamycin-Treated Mice
TJL male | UM male | UT male | Mean male | TJL female | UM female | UT female | Mean female | |
Control, median | 800 | 851 | 780 | 889 | 891 | 843 | ||
Rapamycin, median | 841 | 932 | 888 | 1077 | 1008 | 1006 | ||
% Change | 5 | 10 | 14 | 10 | 21 | 13 | 19 | 18 |
Control, P90 | 1,002 | 1,061 | 985 | 1,064 | 1,061 | 1,101 | ||
Rapamycin, P90 | 1,155 | 1,211 | 1,167 | 1,220 | 1,211 | 1,204 | ||
% Change | 15 | 14 | 18 | 16 | 15 | 14 | 9 | 13 |
Note: Estimates of median survival age or (P90) age at which 90% of the mice had died excluding mice removed from the study as defined in the Methods section. Percent change calculated as (rapamycin − control)/(control). Mean values are averages of the values calculated for each of the three test sites. UT = University of Texas; UM = University of Michigan; TJL = The Jackson Laboratory.