Table 3.

Apparent Cause of Death in Control and Rapamycin-Treated Mice

	Number of cases		Percent of cases		Mean age at death
Diagnosis	Control	Rapamycin	Control	Rapamycin	Control	Rapamycin
Adrenal carcinoma	2		4
Cardiac fibrosis	1		2
Cardiomyopathy		1		2
Fibrosarcoma	3	1	7	2
Hemangiosarcoma	10	6	22	14	884	890
Hydronephrosis		1		2
Liposarcoma		1		2
Liver carcinoma	2	4	4	9	841	1006
Lung carcinoma	7	15	15	34	755	1004
Lymphoma	15	8	33	18	920	951
Mammary carcinoma	4	2	9	5	826	1142
Melanoma		1		2
Mouse urinary syndrome	1		2
Nephritis		1		2
Septicemia		1		2
Skin carcinoma		1		2
Thymoma		1		2
Thyroid carcinoma	1		2
Total diagnosable cases	46	44

Note: Mean age at death is calculated for those diagnostic categories with at least two cases in each of the two groups of mice.