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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Proteins. 2010 Apr;78(5):1331–1337. doi: 10.1002/prot.22666

Figure 3.

Figure 3

Intersubunit contacts of CXCL12 dimers. (a) Arginine zipper motif forms the interactions in the amino terminal regions of the CC-like CXCL12 dimer. Cysteines are colored yellow, arginines from chains A and B are colored purple and red, respectively. (b) Crystallographic packing between CC-dimers. Cartoon representation with semi-transparent surface of two representative chains in the decamer of CXCL12 in between each CC chemokine-like dimer. (c) Overlay of the CC-like dimer of CXCL12 and the CC dimer of CCL5. Chain A from each dimer was aligned. Glutamic acid 15 from CXCL12 and isoleucine 15 from CCL5 are shown as sticks to indicate the 180° rotation of the carbon backbone.