Table 2.
Genes regulated by Ago1 and Rdp1 in the serotype A C. neoformans
| SeroD CnID | SeroA CnID | ScID | Serotype A |
Function (KOG predicted function) | |
|---|---|---|---|---|---|
| ago1Δ/ WTα | rdp1Δ /WTα | ||||
|
Under glucose-rich condition | |||||
| 163.m06442 | 01256 | None | −2.265 | −2.128 | Unknown (Zn-finger protein) |
| 163.m02872 | 01024 | None | −2.20 | −0.392 | Unknown |
| 181.m07823 | 00049 | None | −1.28 | 0.664 | Unknown (Sentrin-specific cystein protease) |
| 162.m02614 | 07779 | YPL069C | 1.159 | 1.17 | D-glycerate 3-kinase |
| 167.m03679 | 02488 | None | 1.31 | 2.546 | Unknown (Methionyl-tRNA formyltransferase) |
| 181.m08143 | 00397 | None | 1.329 | 0.931 | Pyruvate dehydrogenase |
|
Under glucose-starved condition | |||||
| 179.m00054 | 07505 | None | −3.765 | −3.704 | Unknown (Nuclear protein containing WD40 repeat) |
| 181.m08459 | 00738 | None | −1.026 | −1.688 | Unknown (Flavonol reductase/cinnamoyl-CoA reductase) |
| 179.m00600 | 01474 | None | −1.591 | −3.14 | Unknown (Cysteine proteinase Cathepsin L) |
| 180.m00181 | 06629 | None | −1.874 | −0.94 | Unknown (Serine/threonine protein phosphatase 2A) |
| 163.m06474 | 01286 | None | −0.931 | −1.667 | Unknown (Leucine rich repeat proteins) |
| 163.m02895 | 01001 | None | −0.211 | −1.563 | Unknown (Polypeptide release factor 3) |
| 186.m03966 | 04036 | None | −0.054 | −1.514 | Unknown (Heat shock transcription factor) |
| 184.m05097 | 05546 | None | −0.12 | −1.064 | Unknown (Predicted membrane protein) |
| 167.m05909 | 02319 | None | −0.973 | −1.047 | Unknown (DNA-dependent protein kinase) |
| 177.m02995 | 03440 | None | −0.785 | −1.034 | Unknown (Telomerase elongation inhibitor/RNA maturation protein PINX1) |
| 181.m08838 | 00052 | None | 1.039 | 1.186 | Unknown |
| 163.m06568 | 00885 | None | 1.667 | 1.389 | Unknown (Histones H3 and H4) |
Fold increase (ago1Δ/WT or rdp1Δ/WT) is log2 scale.
ScID refers to the gene name in the SGD (Saccharomyces Genome Database)