Table I.
Baseline data and data on RBC regeneration in response to pre-operative autologous blood donation of one or two units.
| 1 PABD | 2 PABD | |
|---|---|---|
| Patients (n) | 439 | 265 |
| EBV (L) | 4.5 ± 07 | 4.8 ± 0.8 |
| Initial Hct (%) | 38.7 ± 3.3** a | 40.0 ± 3.3** b, c |
| d RBC total (mL) | 169.3 ±20.2** | 339.5 ± 35.5** |
| d RBC in 1st PABD (mL) | 169.3 ±20.2** | 176.7 ± 19.3 |
| d RBC in 2nd PABD (mL) | - | 162.8 ± 18.5 |
| Hct at 2nd PABD (%) | - | 37.6 ± 3.1b |
| T1 - S (days) | 21.8 ±9.5**, d | 35.8 ± 8.8** |
| T1 - T2 (days) | - | 16.3 ± 6.0 d |
| T2 - S (days) | - | 19.5 ± 7.3 c |
| Pre-operative Hct (%) | 36.8 ± 2.6** a | 37.1 ± 2.7** c |
| +RBC total (mL) | 109.3 ±85.2** | 250.2 ± 93.0** |
| +RBC to 1st PABD (mL) | 109.3 ±85.2** | 88.8 ± 81.9**, e |
| +RBC to 2nd PABD (mL) | - | 161.4 ± 87.8 e |
| +RBC(% d RBC) | 67.6 ± 53.4* | 75.1 ± 29.4* |
PABD=pre-operative autologous blood donation; EBV=patient's estimated blood volume (calculated); Hct=haematocrit; d RBC=RBC mass deposited by PABD; T1 - S=time-interval between first PABD and surgery; T1 – T2=time interval between first and second PABD; T2 -S=time interval between second PABD and surgery; +RBC=increase (regeneration) of RBC mass in response to PABD; +RBC(% d RBC)=increase in RBC mass calculated as a percentage of RBC mass deposited.
*
p<0.01.
**, a, b, c, d, e
p<0.001. Calculations were based on systemic Hct (systemic Hct=venous Hct x 0.914). Data drawn from Singbartl et al. (2007)21.