Table II.
Increase in RBC-mass to praeoperative autologous blood donation of one and two units in dependence on time-intervall.
| One PABD (n=439) | ||||
| Patients (n) | 124 | 135 | 89 | 91 |
| T1-S (days) | 12.2±2.6 | 18.7±2.2 | 24.9±2.1 | 36.6±6.2 |
| (weeks) | ≤2 | >2–≤3 | >3–≤4 | >4 |
| +RBC (mL) | 58.1±68.9 a | 110.2±71.3 a | 141.0±90.4 a | 146.6±85.2 a |
| +RBC (% d RBC) | 34.3 | 65.1 | 83.3 | 88.6 |
| Two PABD (n=265) | ||||
| Patients (n) | 52 | 80 | 77 | 56 |
| T1 - S (days) | 24.3±4.1 | 32.2±2.0 | 38.9±2.3 | 47.4±7.2 |
| (weeks) | 2* + ≤2 |
2* + >2/≤3 |
2* + >3/≤4 |
2* + >4 |
| +RBC mass (mL) | 199.6 ±101.2 b, c | 244.2±76.9 b | 256.1±95.1 b | 297.4±78.6 c |
| +RBC (% d RBC) | 58.7 | 71.9 | 75.4 | 87.6 |
PABD=pre-operative autologous blood donation; T1 - S=time-interval between first PABD and surgery; +RBC=increase (regeneration) in RBC mass in response to PABD (total); +RBC (% d RBC)=increase in total RBC mass in response to PABD, calculated as a percentage of the RBC mass deposited. 2*=average time-interval between first and second PABD was 16.6 days (2.4 weeks); data are given as mean±SD.
P<0.01 with respect to increase in RBC mass in response to one PABD for the time-interval "T1 - S" of ≤2 weeks versus >2, >3, >4 weeks.
P<0.05 and
P<0.01 with respect to increase in RBC mass in response to two PABD for the time-interval "T1 - S" of 2* + ≤2 weeks versus 2* + >2, 2* + >3, 2* + >4 weeks. Calculations were based on systemic Hct (systemic Hct=venous Hct x 0.914). Data drawn from Singbartl et al. (2007)21.