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. 2011 Jan;9(1):10–18. doi: 10.2450/2010.0088-10

Table III.

Daily RBC regeneration rate in response to PABD of one or two units with respect to time-intervals.

One PABD (n = 439) Two PABD (n = 265)

Time interval
RBC generation (mL/day) P value Within 1 PABD Time interval
RBC generation (mL/day) P value within 2 PABD P value between 1and 2 PABD
(weeks) (days) (weeks) (days)
T1 – S 21.8 ± 9.5 5.2 ± 4.3a, b T1 – S 35.8 ± 8.8 <0.000
T1 – 2 7.2 ± 3.0 <0.001

T1 – T2 16.3 ± 6.0 <0.001
T2 – S 19.5 ± 7.3
T1 – T2 5.6 ± 5.8a <0.001 ns
T2 – S 8.7 ± 5.7b <0.001

T1 – S (<3 weeks) 18.7 ± 2.2 T2 – Sc (<2 weeks) 11.3 ± 3.1 <0.001
T1 – S (>4 weeks) 36.6 ± 6.7 <0.001 T2 – Sd (>4 weeks) 33.0 ± 4.5
5.8 ± 3.7 T2 – S (<2 weeks) 9.8 ± 8.4 <0.05
4.2 ± 3.4 <0.001 T2 – S (>4 weeks) 7.0 ± 2.3

PABD=pre-operative autologous blood donation; T1 – S=time-interval between first PABD and surgery; T1 – T2=time interval between first and second PABD; T2 – S=time interval between second PABD and surgery; ns=not statistically significant. Data are given as mean ± SD;

c, d:

corresponding time-interval ‘T1 – T2’:

b

17.7 ± 6.9 versus

c

15.1 ± 5.8 days; P=ns. Data drawn from Singbartl et al. (2007)21.