Table IV.
Comparison of baseline, time, and efficacy data in patients with an anaemic versus a non-anaemic initial haematocrit level before commencing PABD of one or two units.
| Anaemic (Hct <37%) | Non-anaemic (Hct =37%) | Anaemic (Hct <40%) | Non-anaemic (Hct =40%) | |||
|---|---|---|---|---|---|---|
| One PABD (n = 439) | Female (n = 286) | Male (n = 153) | ||||
| Patients, n (%) | 122 (42.7%) | * | 164 (57.3%) | 64 (41.8%) | * | 89 (58.2%) |
| Initial Hct (%) | 35.0±1.2 | * | 39.5±2.1 | 37.9±1.7 | * | 42.8±2.0 |
| Pre-operative Hct (%) | 34.6±1.7 | * | 36.4±1.8 | 37.5±2.2 | * | 39.9±2.1 |
| Δ Hct (%) (pre-op Hct – initial Hct) | −0.4±1.8 | * | −2.8±1-7 | −0.4±1.5 | * | −2.7±1.9 |
| T1-S (days) | 23.7±10.5 | ns | 21.7± 9.8 | 22.4±7.4 | * | 19.1±8.1 |
| +RBC mass (mL) | 148.3±67.6 | * | 73.8±65.8 | 170.5±81.6 | * | 77.0±93.9 |
| +RBC (% d RBC) | 101±48 | * | 44±39 | 101±48 | * | 40±49 |
| Two PABD (n = 265) | Female (n = 134) | Male (n = 131) | ||||
| Patients, n (%) | 34 (25.4%) | * | 100 (74.6%) | 45 (34.4%) | * | 86 (65.6%) |
| Initial Hct (%) | 35.6±1.0 | * | 39.5±2.0 | 38.0±1.4 | * | 43.4±2.2 |
| Pre-operative Hct (%) | 34.7±1.3 | * | 35.9±2.1 | 36.7±1.8 | * | 39.6±2.3 |
| ÄHct (%) (pre-op Hct – initial Hct) | −0.8±1.5 | * | −3.3±2.2 | −1.1±1.5 | * | −3.4±2.2 |
| T1-S (days) | 36.8±8.2 | ns | 36.5±9.4 | 37.7±8.6 | * | 33.7±8.2 |
| T1-T2 (days) | 17.5±4.7 | ns | 16.8±6.4 | 16.6±5.3 | ns | 15.6±6.8 |
| T2-S (days) | 20.3±6.4 | ns | 19.7±8.0 | 21.2±7.2 | ns | 18.1±6.8 |
| +RBC mass to 1st PABD (mL) | 132.9±78.9 | * | 73.3±71.2 | 104.0±65.1 | ns | 81.5±95.2 |
| +RBC mass to 2nd PABD (mL) | 162.1±82.6 | ns | 152.7±78.3 | 195.4±87.5 | ns | 153.1±97.0 |
| + RBC mass total (mL) | 295.0±58.5 | * | 226.0±79.7 | 299.9±82.5 | * | 234.6±107.5 |
| +RBC(% d RBC) | 100±20 | * | 69±25 | 93±25 | * | 63±29 |
PABD=pre-operative autologous blood donation; Hct=haematocrit; T1-S=time interval between first PABD and surgery; T1-T2=time interval between first and second PABD; T2-S=time interval between second PABD and surgery; +RBC=increase (regeneration) of RBC mass in response to PABD. +RBC(% d RBC)=increase in RBC mass calculated as a percentage of RBC mass deposited. Data are given as mean±SD.
P<0.01 between anaemic and non-anaemic female or male patients who made one or two PABD. ns: non statistically significant. Calculations were based on systemic Hct (systemic Hct=venous Hc tx 0.914). Data drawn from Singbartl et al. (2007)21.