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| IC50a (μM) |
||||||
|---|---|---|---|---|---|---|
| NIH3T3 | TE-71 | MDA-MB-231 | Panc-1 | DU145 | NIH3T3/v-Src | |
| S3I-V3-30 | 420 | >500 | 147.8 ± 5.1 | 74.5 ± 8.4 | 65.1 ± 8.3 | 62.5 ± 3.4 |
| S3I-V3-31 | >500 | >500 | 145.2 ± 4.4 | 175.7 ± 5.3 | 68.6 ± 1.8 | 100.2 ± 2.2 |
| S3I-V3-32 | >500 | >500 | 100.4 ± 3.2 | 77.7 ± 2.7 | 80.2 ± 5.1 | 45.6 ± 3.1 |
| S3I-V3-34 | >500 | >500 | 66.1 ± 2.1 | 77.2 ± 1.9 | 65.3 ± 2.3 | 41.1 ± 4.6 |
| S3I-V4-01 | >500 | >500 | 82.4 ± 1.4 | 197.6 ± 2.1 | 75.4 ± 3.4 | 145.6 ± 6.1 |
IC50 values: Drug concentration at which 50% of cell viability is inhibited.
