TABLE 4.
Cases (n = 99) | Controls (n = 291) | P value2 | |
Matching factors | |||
Age (y) | 61 ± 63 | 61 ± 6 | NA |
Current smoker (%) | 23 | 23 | NA |
History of cardiovascular disease (%) | 40 | 40 | NA |
Cardiovascular disease risk factors | |||
Parental history of coronary disease (%) | 28 | 19 | 0.06 |
History of hypertension (%) | 61 | 45 | 0.01 |
History of diabetes (%) | 21 | 8 | <0.001 |
BMI (kg/m2) | 27.1 ± 5.4 | 26.4 ± 5.0 | 0.29 |
Activity (MET-h/wk) | 16.5 ± 18.9 | 16.6 ± 19.3 | 0.97 |
Drug therapy (%) | |||
Hormone therapy at blood draw | 32 | 37 | 0.36 |
Aspirin use >22 d/mo | 25 | 18 | 0.10 |
Thiazide diuretics | 27 | 16 | 0.02 |
Magnesium supplements | 2 | 3 | 0.75 |
Nutrients | |||
Plasma magnesium (mg/dL) | 2.0 ± 0.2 | 2.1 ± 0.3 | 0.009 |
Magnesium intake (mg/d) | 296 ± 65 | 308 ± 70 | 0.11 |
Potassium intake (mg/d) | 2956 ± 629 | 2934 ± 525 | 0.92 |
Calcium intake (mg/d) | 1023 ± 483 | 1007 ± 498 | 0.78 |
Vitamin D intake (IU/d) | 311 ± 208 | 373 ± 248 | 0.06 |
Omega-3 fatty acid intake (% of energy) | 0.13 ± 0.13 | 0.15 ± 0.14 | 0.29 |
Alcohol (g/d) | 6.5 ± 11.9 | 6.3 ± 12.7 | 0.92 |
MET-h, metabolic equivalent task hours; NA, not applicable.
P values were calculated by using repeated-measures linear regression models (Proc Mixed in SAS; SAS Institute Inc, Cary, NC) for continuous variables and generalized estimating equations for categorical variables.
Mean ± SD (all such values).