TABLE 1.
Genotype frequencies for SHMT1 rs1979277 (1420 C→T) and MTHFR rs1801133 (677 C→T) in the HPFS, 1994–2000 (n = 719) and the NHS, 1990–1998 (n = 652)1
| n |
SHMT1 rs1979277 (1420 C→T) |
MTHFR rs1801133 (677 C→T) |
|||||
| CC | CT | TT | CC | CT | TT | ||
| NHS | % | ||||||
| Cases | 227 | 46.3 | 46.7 | 7.1 | 43.2 | 46.7 | 10.1 |
| Controls | 425 | 48.5 | 43.1 | 8.5 | 48.9 | 41.2 | 9.9 |
| HPFS | |||||||
| Cases | 245 | 49.0 | 44.9 | 6.1 | 42.0 | 48.2 | 9.8 |
| Controls | 474 | 45.6 | 42.4 | 12.0 | 39.0 | 47.7 | 13.3 |
1
Values are percentages for cases and controls, respectively, and are presented separately for each study.