Figure 6.

BAL cytokines and intermediate phenotypes. Shown is a schematic diagram of the relationship between BAL cytokines, intermediate phenotypes indicative of disease processes, and asthma syndromes. Our study informs the best methods for mapping cytokines to distinct intermediate phenotypes using LR and MARS. As the spectrum of intermediate phenotypes are defined and their relationship to severe asthma better understood, this work may be used in clinical study design, prediction of therapeutic response, and ultimately personalized therapy.