Table 3. Immunohistochemical patterns between the normal cornea and the RK case with the markers of corneal epithelial stem/progenitor cells and corneal-type epithelial differentiation.
Normal limbal stem cells | Normal central corneal epithelial cells | Continuously unstable corneal curvatures (central cornea) | |
Krt3 | Negative | Positive | Positive |
Cx43 | Negative | Positive | Positive |
ΔNp63 | Positive | Negative | Positive |
ABCG2 | Positive | Negative | Positive(+++) |
p38 MAPK | Negative | Negative | Positive(+++) |
AP2 | Negative | Negative | Positive |
ERK | Positive (+) | Positive (+) | Positive (+++) |