Table 2. Oral administration of U-Omp19 expressing crude leaf material without adjuvant induces protection against oral B. abortus challenge in BALB/c mice.
| Vaccine (n = 5) | Log10 a CFU of B. abortus 2308 at spleen (mean ± SD) | Units of protection |
| N. benthamiana– U-Omp19 | 4.07±0.36 b | 1.45 |
| N. benthamiana –wt | 5.59±0.04 c | −0.07 |
| U-Omp19 purified from E. coli | 4.37±0.21 b | 1.15 |
| PBS | 5.52±0.09 c | 0 |
a
The content of bacteria in spleens is represented as the mean log10 CFU ± SD per group.
b
Significantly different from PBS-immunized mice P<0.01 estimated by Dunnett's test.
c
Significantly different from U-Omp19 immunized mice P<0.01 estimated by Dunnett's test.