Table 3. Protection against oral B. abortus infection in BALB/c mice vaccinated orally with L-Omp19 or U-Omp19 without adjuvants or with U-Omp19+CT.
| Vaccine (n = 5) | Adjuvant | Log10 a CFU of B. abortus 2308 at spleen (mean ± SD) | Units of protection |
| L-Omp19 | None | 4.36±0.07 c | 1.03 |
| U-Omp19 | CT | 4.13±0.31 b | 1.26 |
| U-Omp19 | None | 4.35±0.19 b | 1.04 |
| B. abortus RB51 | None | 3.91±0.64 b | 1.48 |
| PBS | None | 5.39±0.16 d | 0 |
a
The content of bacteria in spleens is represented as the mean log10 CFU ± SD per group.
b
Significantly different from PBS-immunized mice P<0.01 estimated by Dunnett's test.
c
Significantly different from PBS-immunized mice P<0.05 estimated by Dunnett's test.
d
Significantly different from B. abortus RB51 immunized mice P<0.01 estimated by Dunnett's test.