Table 4. Parenteral L-Omp19 or U-Omp19 inoculation without adjuvant induce protection against B. abortus infection in BALB/c mice.
Vaccine (n = 5) | Adjuvant | Log10 a CFU of B. abortus 544 at spleen (mean ± SD) | Units of protection |
L-Omp19 | None | 4.72±0.62 b, d | 1.56 |
U-Omp19 | None | 4.44±0.26 b | 1.84 |
U-Omp19 | IFA | 4.48±0.13 b | 1.80 |
B. abortus S19 | None | 4.01±0.27 b | 2.27 |
PBS | None | 6.28±0.13 c | 0 |
The content of bacteria in spleens is represented as the mean log10 CFU ± SD per group.
Significantly different from PBS-immunized mice P<0.01 estimated by Dunnett's test.
Significantly different from B. abortus S19 immunized mice P<0.01 estimated by Dunnett's test.
Significantly different from B. abortus S19 immunized mice P<0.05 estimated by Dunnett's test.