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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Bone. 2010 Sep 24;48(2):275–280. doi: 10.1016/j.bone.2010.09.028

Figure 1. MicroCT analysis of trabecular bone in the Ts65Dn femur.

Figure 1

MicroCT images of the distal femur in euploid and trisomic mice at the ages of 6 and 16 weeks (A). Analysis revealed a significant reduction in percent bone volume (B) and number of trabeculae (C), as well as a significant increase in trabecular separation (D) at both time points in trisomic mice. Although smaller, no significant difference was found in trabecular thickness (E) between the two groups. (Eu 6 wks, n= 12; Ts 6 wks, n= 10; Eu 16 wks, n= 10; Ts 16 wks, n= 16) (*p ≤ 0.05, **p ≤ 0.01, *** p ≤ 0.001)