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. Author manuscript; available in PMC: 2012 Feb 1.

Published in final edited form as: Bone. 2010 Sep 24;48(2):275–280. doi: 10.1016/j.bone.2010.09.028

Table 1. Densitometry analysis reveals altered bone composition in Ts65Dn mice.

	6 Weeks of Age		16 Weeks of Age
	Euploid	Trisomic	Euploid	Trisomic
Femur	n=18	n=16	n=17	n=22
Area (cm²)	0.411 (0.015)	0.374 (0.013)^*	0.536 (0.012)	0.458 (0.010)^***
BMD (g/cm²)	0.059 (0.002)	0.046 (0.001)^***	0.071 (0.001)	0.065 (0.002)^*
BMC (g)	0.025 (0.001)	0.017 (0.001)^***	0.038 (0.001)	0.030 (0.001)^***
Skull	n=7	n=16	n=10	n=9
Area (cm²)	2.241 (0.038)	2.008 (0.025)^***	2.475 (0.034)	2.281 (0.032)^***
BMD (g/cm²)	0.099 (0.002)	0.094 (0.002)^*	0.118 (0.002)	0.110 (0.003)^**
BMC (g)	0.222 (0.007)	0.188 (0.004)^***	0.292 (0.004)	0.252 (0.008)^***

Data are presented mean ± (SEM).

^*

p ≤ 0.05

^**

p ≤ 0.01

^***

p ≤ 0.001