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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2010 Nov 10;24(1):187–196. doi: 10.1111/j.1755-148X.2010.00788.x

Figure 3.

Figure 3

XANES spectra reveal that mutations in both Gpnmb and Tyrp1 contribute to differences between C57BL/6J and DBA/2J melanosomes. (A) Strain-dependent spectral difference exhibited by melanosomes of C57BL/6J and DBA/2J mice. (B) Monogenic contributions of Gpnmb and Tyrp1 mutations. Normalized spectra, mean ± 1 standard deviation; Student’s two-tailed t-test (compared to C57BL/6J) with significance set at 0.05 (red bar); n = number of fields analyzed per genotype.