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Conformations of the LBD core-dimer. Monomers are shown using a ribbon representation colored gray or blue. Bound glutamate is shown using spacefilling (CPK) representation in (A) the active, glutamate bound and (B) desensitized, glutamate bound. (C) Resting, apo, and (D) A “desensitized-like” state. (Dotted lines) S740 Cα-Cα distances.
