Table 3.
Effect of aqueous extract of Ficus bengalensis on MDA and NO content, SOD activity and mast cell degranulation in TNBS-induce inflammatory bowel disease in rats
| Groups | MDA (nmole/mg of protein) | NO (nmole/mg of protein) | SOD (U/min/mg of protein) | Mast cell degranulation (% protection) |
|---|---|---|---|---|
| Control | 17 ± 0.7 | 12 ± 0.5 | 0.89 ± 0.05 | 80 ± 1.5 |
| Model | 88 ± 2.1* | 28 ± 1.1* | 0.22 ± 0.03* | 8 ± 0.5* |
| Prednisolone | 34 ± 1.4# | 14 ± 0.8# | 0.78 ± 0.05# | 62 ± 1.0# |
| AEFB (250 mg/kg) | 50 ± 1.7# | 20 ± 0.5# | 0.7 ± 0.02# | 45 ± 0.8# |
| AEFB (500 mg/kg) | 38 ± 1.8# | 16 ± 0.6# | 0.62 ± 0.03# | 54 ± 0.9# |
(MDA: malondialdehyde, NO: nitric oxide, SOD: superoxide dismutase), Each value presented as mean ± SEM (n=6) (one-way ANOVA). Compared with the control group P<0.001
#
Compared with the model group P<0.001.