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AMD3100 exerts biphasic effects on apoptosis induced by serum deprivation in myeloma cells. RPMI8226 cells were incubated with or without AMD3100 in RPMI-1640 medium for up to 14 days. At indicated time points, apoptosis of the cells were analyzed by flow cytometry after staining with annexin V and propium iodide (PI). Representative results of three independent experiments showing consistent results are shown.
