Table III.
Baseline Characteristics of SARP Participants who enrolled at Age of 40 Years and above by Racial Background & Phenotype Group
| Both Races N=398 |
Black n=105 (26.4%) |
White n=293 (73.4%) |
||||
|---|---|---|---|---|---|---|
| Mild/Mod n=166 |
Severe n=232 |
Mild/Mod n=45 |
Severe n=60 |
Mild/Mod n=121 |
Severe n=172 |
|
| *Age at Diagnosis (yrs) | 18(5,36) | 20(5.5,35) | 18(5,35) | 13(3.5,33.5) | 18(6,38) | 21(6.5,35) |
| Duration of Asthma (yrs) | 31.6(11.2,42.3) | 29.9(15.8,45.3) | 25.9(11.2,39.6) | 31.9(15.3,43.5) | 32(11.2,42.7) | 29.4(16.5,46.4) |
| *BMI (kg/m2) | 29.1(25.8,34.9) | 30.8(26,35.2) | 32.9(28.3,38.2) | 32.9(26.9,36.9) | 28.4(24.6,32.9) | 30(25.8,34.3) |
| Baseline Predrug FEV1 (liters) | 2.31(1.81,2.73) | 1.74(1.26,2.26) | 1.84(1.69,2.31) | 1.71(1.30,2.18) | 2.45(2.00,2.89) | 1.77(1.24,2.34) |
| *Baseline Predrug FEV1% Pred | 78(66,87) | 57(44,75) | 73(57,86) | 64.5(48.5,85.5) | 79(66,88) | 56(42,71) |
| *Baseline Predrug FVC% Pred | 85(76,94) | 73.6(60,84) | 83(72.3,91) | 79(66.8,97) | 86(77,94) | 72(58,82) |
| *FEV1/FVC | 0.73(0.65,0.78) | 0.65(0.54,0.72) | 0.73(0.64,0.76) | 0.67(0.3,0.72) | 0.72(0.66,0.78) | 0.63(0.53,0.72) |
| Max FEV1 Reversal (%) | 11.5(7.1,20.2) | 13.8(6.3,24.5) | 13.1(6.8,20.7) | 15.4(7.5,25.7) | 11(7.1,19.4) | 13.7(6,24) |
| *Log IgE (IU/ml) | 1.94(1.46,2.36) | 2.00(1.44,2.49) | 2.14(1.73,2.64) | 2.29(1.83(2.72) | 1.90(1.43,2.31) | 1.93(1.34,2.36) |
| Atopy | 122(73.5%) | 136(58.6%) | 33(73.3%) | 34(56.7%) | 89(73.6%) | 102(59.3%) |
| ≥5 Positive Skin Tests | 44(26.5%) | 40(17.2%) | 16(35.6%) | 12(20%) | 28(23.1%) | 28(16.3%) |
| *Female | 107(64.5%) | 148(63.8%) | 30(66.7%) | 44(73.3%) | 77(63.6%) | 104(60.5%) |
| Currently Employed | 125(75.3%) | 144(62.1%) | 30(66.7%) | 33(55%) | 95(78.5%) | 111(64.5%) |
| Diagnosed Diabetes | 12(7.2%) | 31(13.4%) | 3(6.7%) | 9(15%) | 9(15%) | 22(12.8%) |
| Diagnosed Hypertension | 37(22.3%) | 72(31%) | 13(28.9%) | 19(31.7%) | 19(31.7%) | 53(30.8%) |
| *Diagnosed GERD | 49(29.5%) | 98(42.4%) | 12(26.7%) | 20(33.3%) | 37(30.6%) | 78(45.3%) |
*
Mean age: 51.3 ± 7.86
Continuous variables: median (25th, 75th percentiles); Categorical variables: n (%)
FEV1: forced expiratory volume in one second
FVC: forced vital capacity ratio
GERD: gastroesophageal reflux disease.
2ndhand smoke exp: secondhand smoke exposure
*
p < 0.15 Black severe vs White severe.