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. 2011 Jan 17;6(1):e15964. doi: 10.1371/journal.pone.0015964

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Hao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Orthologous genes existed in each pair of strains and in all three strains of Lb. bulgaricus are counted and shown in corresponding sectors. Three types of orthologous genes were counted and illustrated in the parentheses from left to right: genes with identical DNA sequence, genes with synonymous variations, and genes with amino acid variations. Each orthologous gene pair was identified based on the best Blast hit (BBH) approach. The numbers in the white square frames represent the percentage value of hypothetical genes in each category. The numbers in the non-overlap segments of Venn Diagram represent the number of non-orthologous genes specific to each of the three strains, consisting of two types, unique vs. duplicated. The numbers in the yellow square frames represent the percentage value of pseudogenes in each strain. The numbers in the outside frames of the diagram represent the numbers of the annotated (known function) genes and hypothetical genes in the part of non-orthologous genes specific to each strain.