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. 2011 Jan 17;6(1):e14526. doi: 10.1371/journal.pone.0014526

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Ringvall et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Tumors were dissected and measured. Tumor volumes were calculated by the formula ((π/6)×width²×length). Each dot represents the summarized tumor volume in mm³ from one mouse at (A) 12 weeks of age (n^+/+ = 16; n^−/− = 16) and at (B) 15 weeks of age (n^+/+ = 11; n^−/− = 12). Statistical analyses were performed with a two-tailed Mann-Whitney test, vertical bars represent standard deviation, * p≤0.05.