Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jan 17;6(1):e14526. doi: 10.1371/journal.pone.0014526

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Ringvall et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Collagen, thrombin and ADP-induced platelet aggregation in PRP from HRG^+/+ and HRG^−/− mice on a pure C57BL/6 (B6) or on a mixed 129/Ola, C57BL/6 (129/B6) genetic background was measured with an aggregometry assay. Aggregation levels are represented by light transmission through PRP over time. (B–C) Flow cytometric analyses of thrombin- and ADP- induced activation of platelets presented by mean fluorescent intensity (MFI). Ligands were added at time = 0. Each symbol (squares = HRG^+/+, open triangles = HRG^−/−) represents the mean value from three independent measurements. Vertical bars represent standard deviation. (B) P-selectin after activation with 0,01 U/ml thrombin measured at 0, 1, 3, 5 and 10 minutes. (C) Activated fibrinogen receptor (GPIIb/IIIa) after 15 minutes stimulation with 1 or 10 µM ADP.