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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Clin Immunol. 2010 Oct 12;138(1):60–66. doi: 10.1016/j.clim.2010.09.008

Fig. 3.

Fig. 3

Hnrph3 is an AAU-relevant autoantigen. (A) Hnrph3-phage binding to patient IgGs versus control IgGs. Bound phages were quantified by plaque assay. (B) ROC curve analysis summarizing sensitivities and specificities of the binding results in (A) to identify patients versus controls with area under the curve of 0.624 (SE=0.079). A significant difference was detected between the mean logarithms of the test values (p=0.007, unpooled variance t-test). With an assumed specificity of ~70%, the expected sensitivity of Hnrph3 as an AAU biomarker is ~65%. The diagonal segments are produced by ties.