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Schematic model of hepatitis B surface antigen structure. Three forms of hepatitis B surface (HBs) antigen (Dane particle, filamentous particle, and spherical particle) are visualized in serum by electron microscopy. These are composed of small, middle, and large hepatitis B surface proteins. LHBs: Large HBs proteins; MHBs: Middle HBs proteins; SHBs: Small HBs proteins.
