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. 2011 Jan 21;17(3):334–342. doi: 10.3748/wjg.v17.i3.334

Table 2.

Bone mineral density of spine and femur, in- and between-group change

Lumbar spine Baseline First year Second year Third year
Group A calcium/vitamin D n (%) 32 27 (84.4) 22 (68.6) 14 (43.8)
T-score -1.57 ± 0.31 -1.32 ± 0.42b -1.21 ± 0.49b -1.18 ± 0.36b
Δ T-score (95% CI) +0.28 ± 0.35 (0.162–0.460) +0.33 ± 0.49 (0.109-0.558) +0.43 ± 0.47 (0.147–0.708)
BMD 0.90 ± 0.04 0.92 ± 0.05 0.94 ± 0.05 0.94 ± 0.04
Group B + sodium fluoride n (%) 62 47 (75.8) 36 (58.0) 30 (48.4)
T-score -1.82 ± 0.75h -1.60 ± 0.84d -1.40 ± 1.01d -1.37 ± 0.95d
Δ T-score (95% CI) +0.22 ± 0.33 (0.125–0.321) +0.47 ± 0.60 (0.262–0.676) +0.51 ± 0.44 (0.338–0.682)
BMD 0.87 ± 0.08 0.88 ± 0.09 0.90 ± 0.11 0.91 ± 0.11
Group C + ibandronate n (%) 54 49 (90.1) 34 (63.0) 27 (50)
T-score -1.89 ± 0.71 -1.69 ± 0.78e -1.61 ± 0.83e -1.56 ± 0.78f
Δ T-score (95% CI) +0.22 ± 0.38 (0.111– 0.329) +0.36 ± 0.53 (0.147–0.578) +0.41 ± 0.48 (0.238–0.576)
BMD 0.85 ± 0.08 0.87 ± 0.08 0.89 ± 0.08 0.90 ± 0.08
Total n (%) 148 123 (83.1) 92 (62.2) 71 (47.8)

In-treatment group change, baseline to first, second and third year: Group A, bP < 0.01; group B, dP < 0.01; group C, eP < 0.025, fP < 0.01; Between-treatment groups: hP < 0.01, group A vs group C. BMD: Bone mineral density.