Table 2.
LV geometry and other echocardiographic parameters at baseline and year 7 by their geometry at year 7*
| n (%) or mean (±SD) | Normal, n=178 (63%) | Concentric remodeling, n= 87 (31%) | Concentric hypertrophy, n= 8 (3%) | Eccentric hypertrophy, n= 11 (4%) | |||||
|---|---|---|---|---|---|---|---|---|---|
| Year 0 | Year 7 | Year 0 | Year 7 | Year 0 | Year 7 | Year 0 | Year 7 | ||
| Baseline concentric remodeling (n=284) | LV end-diastolic dimension (cm) | 4.2 (±0.4) | 4.7 (±0.5) | 4.1 (±0.4) | 4.1 (±0.4) | 4.3 (±0.5) | 5.0 (±0.5) | 4.5 (±0.3) | 5.5 (±0.5) |
| LV mass (gram) | 141 (±32) | 132 (±33) | 133 (±35) | 137 (±35) | 151 (±53) | 236 (±67) | 157 (±26) | 205 (±27) | |
| LV fractional shortening (%) | 44.8 (±7.7) | 42.9 (±7.7) | 46.8 (±6.6) | 43.4 (±8.4) | 40.6 (±12.4) | 43.7 (±10.0) | 41.7 (±6.5) | 33.4 (±16.0) | |
| LV systolic dysfunction** | 3 (1%) | 6 (4%) | 3 (1%) | 4 (5%) | 1 (1%) | 2 (25%) | 2 (1%) | 4 (36%) | |
| n (%) or mean (±SD) | Normal, n=17 (29%) | Concentric remodeling, n= 14 (24%) | Concentric hypertrophy, n= 13 (22%) | Eccentric hypertrophy, n= 15 (25%) | |||||
| Year 0 | Year 7 | Year 0 | Year 7 | Year 0 | Year 7 | Year 0 | Year 7 | ||
| Baseline concentric hypertrophy (n=59) | LV end-diastolic dimension (cm) | 5.0 (±0.3) | 5.1 (±0.4) | 4.6 (±0.5) | 4.1 (±0.4) | 5.1 (±0.6) | 4.8 (±0.3) | 4.8 (±0.4) | 5.5 (±0.6) |
| LV mass (gram) | 222 (±41) | 164 (±35) | 218 (±44) | 167 (±32) | 251 (±60) | 238 (±45) | 233 (±59) | 229 (±60) | |
| LV fractional shortening (%) | 41.7 (±7.2) | 36.6 (±8.6) | 42.7 (±8.5) | 39.7 (±7.0) | 41.6 (±6.2) | 48.6 (±10.5) | 41.0 (±10.2) | 37.1 (±11.7) | |
| LV systolic dysfunction** | 1 (1%) | 4 (24%) | 1 (1%) | 1 (2%) | 1 (1%) | 0 (0%) | 3 (1%) | 6 (43%) | |
*
LV structure at year 7 was categorized as normal (RWT ≤0.42 and no LVH), concentric remodeling (RWT >0.42 and no LVH), concentric hypertrophy (RWT >0.42 and LVH) and eccentric hypertrophy (RWT ≤0.42 and LVH)
**
Defined as LV ejection fraction <55% as qualitatively assessed on a baseline echocardiogram