Table 3.

Association of baseline characteristics with incident eccentric left ventricular (LV) hypertrophy in older adults with baseline concentric LV geometry

Variable	Eccentric LV hypertrophy at year 7		Unadjusted odds ratio (95% CI); p value	Adjusted odds ratio (95% CI); p value
	No	Yes
Age ≥75 years	105 (33%)	10 (39%)	1.26 (0.55–2.88); p=0.580	1.11 (0.46–2.69); p=0.823
Female	199 (63%)	18 (9%)	1.33 (0.56–3.16); p=0.513	1.94 (0.75–5.02); p=0.169
African American	24 (8%)	2 (8%)	1.02 (0.23–4.57); p=0.982	0.85 (0.18–4.05); p=0.840
Hypertension	147 (46%)	16 (62%)	1.85 (0.82–4.20); p=0.141	0.92 (0.38–2.25); p=0.856
Previous acute myocardial infarction	12 (4%)	4 (15%)	4.62 (1.38–15.52); p=0.013	4.73 (1.16–19.32); p=0.031
Intercurrent acute myocardial infarction	16 (5%)	2 (8%)	1.57 (0.34–7.22); p=0.564	2.22 (0.36–13.60); p=0.388
Intercurrent heart failure	27 (9%)	4 (15%)	1.95 (0.63–6.08); p=0.248	0.84 (0.22–3.24); p=0.800
LV mass indexed for height >39* g/m2.7	133 (42%)	24 (92%)	16.60 (3.88–71.46); p<0.001	17.52 (3.91–78.47); p<0.001
Relative wall thickness >0.46*	157 (50%)	15 (58%)	4.42 (1.60–12.18); p=0.004	1.09 (0.46–2.58); p=0.854

^*Cutoffs based on median values