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. 2011 Feb;164(2):247–252. doi: 10.1530/EJE-10-0792

Table 2.

Inclusion of perinatal data and parental diabetes. The variables in the table may be responsible for some of the effects on type 1 diabetes risk falsely ascribed to the presence of autoantibodies, i.e. may be confounders.

Variables Hazard ratio (HR) 95% CI P<
Tenfold increase in RU  autoantibodies 2.23 1.66–3.01 0.0001
Birth length – per cm 0.91 0.97–1.04 0.91
Birth weight – per kg 1.03 0.87–1.23 0.71
Gestational age – per week 1.00 0.95–1.04 0.84
Maternal age – per 10 years 1.22 1.02–1.489 0.03
Paternal age – per 10 years 0.93 0.80–1.09 0.37
Sex, male versus female 1.05 0.93–1.20 0.42
Maternal type 1 diabetes 4.23 2.29–7.81 0.0001
Paternal type 1 diabetes 7.31 4.71–11.35 0.0001

By inclusion into the statistical model, the individual increases/decreases in type 1 diabetes risk belonging to each variable are listed including the level of significance (P value) and confidence interval (CI).