Table 2.
Inclusion of perinatal data and parental diabetes. The variables in the table may be responsible for some of the effects on type 1 diabetes risk falsely ascribed to the presence of autoantibodies, i.e. may be confounders.
| Variables | Hazard ratio (HR) | 95% CI | P< |
|---|---|---|---|
| Tenfold increase in RU autoantibodies | 2.23 | 1.66–3.01 | 0.0001 |
| Birth length – per cm | 0.91 | 0.97–1.04 | 0.91 |
| Birth weight – per kg | 1.03 | 0.87–1.23 | 0.71 |
| Gestational age – per week | 1.00 | 0.95–1.04 | 0.84 |
| Maternal age – per 10 years | 1.22 | 1.02–1.489 | 0.03 |
| Paternal age – per 10 years | 0.93 | 0.80–1.09 | 0.37 |
| Sex, male versus female | 1.05 | 0.93–1.20 | 0.42 |
| Maternal type 1 diabetes | 4.23 | 2.29–7.81 | 0.0001 |
| Paternal type 1 diabetes | 7.31 | 4.71–11.35 | 0.0001 |
By inclusion into the statistical model, the individual increases/decreases in type 1 diabetes risk belonging to each variable are listed including the level of significance (P value) and confidence interval (CI).